Mycobacterium tuberculosis accounts for 5.9% of central nervous system infection which may take 1 of 3 clinicopatholgical forms including tubercular meningitis, Central Nervous System tuberculoma and spinal arachnoiditis. This case series reports three cases of extrapulmonary nervous system tuberculosis accounting for approximately 1–2% of all Tuberculosis cases and 10% of musculoskeletal TB cases. Incidence rates in immunocompetent versus immunocompromised individuals significantly varies but increasing number of immunocompetent individuals being affected by the diseases has increased over the past decade presenting in unusual locations.We report cases involving three immunocompetent patients diagnosed with extra- pulmonary tuberculosis found in the rare locations and presented with varying clinicalpresentations. All patients underwent standard medical therapy and individualized surgical interventions based on disease location and severity.